CALL FOR PAPERS Real-time Visualization of Lung Function: from Micro to Macro Lung volume quantified by MRI reflects extracellular-matrix deposition and altered pulmonary function in bleomycin models of fibrosis: effects of SOM230
نویسندگان
چکیده
Christine Egger, Christelle Gérard, Nella Vidotto, Nathalie Accart, Catherine Cannet, Andrew Dunbar, Bruno Tigani, Alessandro Piaia, Gabor Jarai, Elizabeth Jarman, Herbert A. Schmid, and Nicolau Beckmann Novartis Institutes for BioMedical Research, Analytical Sciences and Imaging, Basel, Switzerland; University of Basel, Biocenter, Basel, Switzerland; Novartis Institutes for BioMedical Research, Preclinical Safety, Basel, Switzerland; Novartis Institutes for BioMedical Research, Respiratory Diseases Department, Horsham, United Kingdom; and Novartis Institutes for BioMedical Research, Oncology Department, Basel, Switzerland
منابع مشابه
Lung volume quantified by MRI reflects extracellular-matrix deposition and altered pulmonary function in bleomycin models of fibrosis: effects of SOM230.
Idiopathic pulmonary fibrosis is a progressive and lethal disease, characterized by loss of lung elasticity and alveolar surface area, secondary to alveolar epithelial cell injury, reactive inflammation, proliferation of fibroblasts, and deposition of extracellular matrix. The effects of oropharyngeal aspiration of bleomycin in Sprague-Dawley rats and C57BL/6 mice, as well as of intratracheal a...
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